在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 試劑盒
  3. 酶聯免疫試劑盒
  4. Human Calponin-1(CNN1)ELISA Kit

Human Calponin-1(CNN1)ELISA Kit

  • 中文名稱：
    人調寧蛋白- 1(CNN1)酶聯免疫試劑盒
  • 貨號：
    CSB-E14109h
  • 規格：
    96T/48T
  • 價格：
    ￥3600/￥2500
  • 其他：

產品詳情

  • 產品描述：
    人調寧蛋白- 1(CNN1)酶聯免疫試劑盒（CSB-E14109h）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿樣本中的CNN1含量。試劑盒檢測范圍為0.156 ng/mL-10 ng/mL，本產品適用于基礎醫學研究、藥效評估及疾病機制探索等科研場景，為心血管病理研究、抗纖維化藥物開發及腫瘤微環境分析提供可靠檢測工具。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
  • 別名：
    Basic calponin ELISA Kit; Calponin 1 ELISA Kit; Calponin 1 basic smooth muscle ELISA Kit; Calponin H1 ELISA Kit; Calponin H1 smooth muscle ELISA Kit; Calponin-1 ELISA Kit; Calponin1 ELISA Kit; Calponins basic ELISA Kit; CNN 1 ELISA Kit; Cnn1 ELISA Kit; CNN1_HUMAN ELISA Kit; Epididymis secretory protein Li 14 ELISA Kit; HEL S 14 ELISA Kit; Sm Calp ELISA Kit; SMCC ELISA Kit; smooth muscle ELISA Kit
  • 縮寫：
    CNN1
  • Uniprot No.：
  • 種屬：
    Homo sapiens (Human)
  • 樣本類型：
    serum, plasma
  • 檢測范圍：
    0.156 ng/ml-10 ng/ml
  • 靈敏度：
    0.039 ng/mL
  • 反應時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領域：
    Cardiovascular
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%      
    Three samples of known concentration were tested twenty times on one plate to assess.  
    Inter-assay Precision (Precision between assays): CV%<10%      
    Three samples of known concentration were tested in twenty assays to assess.    
                 
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of Human CNN1 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
      Sample Serum(n=4)  
    1:1 Average % 87  
    Range % 84-92  
    1:2 Average % 95  
    Range % 90-99  
    1:4 Average % 94  
    Range % 85-99  
    1:8 Average % 104  
    Range % 98-108  
  • 回收率：
    The recovery of Human CNN1 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample Type Average % Recovery Range  
    Serum (n=5) 92 87-98  
    EDTA plasma (n=4) 87 83-94  
                 
                 
  • 標準曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    ng/ml OD1 OD2 Average Corrected  
    10 2.255 2.345 2.300 2.202  
    5 1.715 1.756 1.736 1.638  
    2.5 1.064 1.024 1.044 0.946  
    1.25 0.523 0.515 0.519 0.421  
    0.625 0.334 0.324 0.329 0.231  
    0.312 0.251 0.234 0.243 0.145  
    0.156 0.162 0.159 0.161 0.063  
    0 0.097 0.098 0.098    
  • 數據處理：
  • 貨期：
    3-5 working days

產品評價

靶點詳情

  • 功能：
    Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
  • 基因功能參考文獻：
    1. Studied maternal serum calponin 1 levels in the prediction of delivery within 7 days among pregnancies complicated with threatened preterm labor. Of 73 women included in the study, found the maternal serum calponin 1 level was significantly high in women who delivered within 7 days vs. those who delivered after 7 days. PMID: 28068849
    2. Loss of myoepithelial calponin was specifically associated with gain of the basal marker p63 in adjacent tumor cells. PMID: 26343330
    3. Loss of CNN1 expression is associated with Ovarian Cancer. PMID: 26504022
    4. CNN1 immunohistochemical staining allows ready recognition of intracytoplasmic inclusions, aiding diagnosis of infantile digital fibromatosis. PMID: 24117680
    5. epsilonPKC/ERK/mTOR pathway activation induced by the rescued expression of CNN1 contributed to the improvement of cardiac dysfunction and pathological changes observed in transgenic mice. PMID: 24631115
    6. Calponin knockdown inhibits autophosphorylation. PMID: 24350264
    7. Expression of transforming growth factor-beta (4.3 +/- 1.4 vs 2.6 +/- 2.3, p = 0.01) and calponin (3.7 +/- 0.7 vs 0.6 +/- 1.1, p = 0.05) was lower from infants with vs without a PDA. PMID: 23731614
    8. Calponin-1 expression in the uterine smooth muscle tissue of the body and the lower uterine segment of smooth muscle tissues was significantly different. PMID: 21051832
    9. Inhibition of calponin-1 expression can inhibit uterine smooth muscle cell migration and cause the morphological change and rearrangement of F-actin without affecting its proliferation and apoptosis in vitro. PMID: 20584679
    10. A single intronic CArG element is necessary but insufficient for proper CNN1 expression in vivo. CNN1 overexpression antagonizes arterial injury-induced neointimal formation. PMID: 21817093
    11. D2-40 immunohistochemistry reliably identifies the myoepithelial cells of breast in a variety of lesions in a pattern similar to that of calponin and p63. PMID: 21326813
    12. The point mutation S175T exhibited more resistance to actin rearrangement by cytochalasin D and PDBu than intact CNh1, suppressing cell motility induced by PDBu. PMID: 20530411
    13. expression in tumor vessels is a new and useful means to predict prognosis of hepatocellular carcinoma after hepatic resection PMID: 11920541
    14. results suggest that regulation of h1-calponin is involved in the regulation of differentiation of AR42J cells into insulin-producing cells PMID: 12606518
    15. the calponin homology domain of Vav1 associates with calmodulin and is prerequisite to T cell antigen receptor-induced calcium release in Jurkat T lymphocytes PMID: 17550897
    16. analysis of distinct sites of interaction that form the calponin: gelsolin complex and two calcium switches that control its activity PMID: 17556051
    17. expression of vascular CNN1 in the peripheral region of colon cancer tissues was significantly reduced in association with tumor progression, lymphatic invasion, vascular invasion and recurrence. PMID: 17707120
    18. Calponin and alpha-inhibin are the most useful positive markers for serous microcystic adenoma, and are negative in most entities in the differential diagnosis. PMID: 19391217

    顯示更多

    收起更多

  • 蛋白家族：
    Calponin family
  • 組織特異性：
    Smooth muscle, and tissues containing significant amounts of smooth muscle.
  • 數據庫鏈接：

    HGNC: 2155

    OMIM: 600806

    KEGG: hsa:1264

    STRING: 9606.ENSP00000252456

    UniGene: Hs.465929



主站蜘蛛池模板： 亚洲国产99精品国自产拍| 揄拍成人国产精品视频| 老熟女毛茸茸浓毛| 日本熟妇人妻中出| 久久久久久a亚洲欧洲av| 精品麻豆国产色欲色欲色欲www| 伊人久久大香线蕉av仙人| 久久久久国色av免费观看| 亚洲国产精品嫩草影院| 免费人成年激情视频在线观看| 香蕉噜噜噜噜私人影院| 亚洲综合激情七月婷婷| 亚洲日韩国产av无码无码精品| 人人爽人人澡人人高潮| 国产精品jk白丝在线播放| 国产亚洲精品一区在线播放| 亚洲第一无码专区天堂| 麻豆日产精品卡2卡3卡4卡5卡 | 欧美又粗又大又硬又长又爽视频| 人妻老妇乱子伦精品无码专区| 中文字幕人妻丝袜二区| 免费午夜爽爽爽www视频十八禁| 2017亚洲天堂最新地址| 天天摸夜夜摸夜夜狠狠添| 精品蜜臀久久久久99网站| 亚洲欧美日韩精品色xxx| 欧美黑人xxxx又粗又长| 国产精品自在拍首页视频| 无码av一区二区三区无码| 欧美一性一乱一交一视频| 国内精品久久久久久久影院| 日本少妇春药特殊按摩3| 成人内射国产免费观看| 欧美日激情日韩精品嗯| 蜜桃mv在线播放免费观看视频| 亂倫近親相姦中文字幕| 特级a欧美做爰片三人交| 色琪琪丁香婷婷综合久久| 男女做爰猛烈叫床视频免费| 又黄又爽又高潮免费毛片| 国产性夜夜春夜夜爽免费下载|