在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 試劑盒
  3. 酶聯免疫試劑盒
  4. Human B-cell differentiation antigen CD72(CD72) ELISA kit

Human B-cell differentiation antigen CD72(CD72) ELISA kit

  • 中文名稱：
    人B細胞分化蛋白CD72(CD72)酶聯免疫試劑盒
  • 貨號：
    CSB-EL004955HU
  • 規格：
    96T/48T
  • 價格：
    ￥3600/￥2500
  • 其他：

產品詳情

  • 產品描述：
    人B細胞分化蛋白CD72(CD72)酶聯免疫試劑盒（CSB-EL004955HU）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的CD72含量。CD72是重要靶點，它是B細胞表面糖蛋白，在B細胞發育、活化及免疫調節中起關鍵作用。研究機制方面，聚焦于其與配體相互作用，通過信號通路影響B細胞功能，針對它的研究有望為免疫相關疾病如自身免疫病、腫瘤等治療帶來新策略。試劑盒檢測范圍為0.9 ng/mL-60 ng/mL，適用于科研領域探究B細胞相關免疫機制，如系統性紅斑狼瘡、類風濕性關節炎等自身免疫疾病模型中的B細胞功能研究，或腫瘤微環境中B淋巴細胞活化狀態的分子機制分析，為免疫調控網絡研究提供定量檢測方案。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
  • 別名：
    CD72; B-cell differentiation antigen CD72; Lyb-2; CD antigen CD72
  • 縮寫：
  • Uniprot No.：
  • 種屬：
    Homo sapiens (Human)
  • 樣本類型：
    serum, plasma, tissue homogenates
  • 檢測范圍：
    0.9 ng/mL-60 ng/mL
  • 靈敏度：
    0.225 ng/mL
  • 反應時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領域：
    Immunology
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of human CD72 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    　 Sample Serum(n=4)
    1:1 Average % 98
    Range % 92-103
    1:2 Average % 91
    Range % 86-98
    1:4 Average % 92
    Range % 88-97
    1:8 Average % 101
    Range % 96-15
  • 回收率：
    The recovery of human CD72 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample Type Average % Recovery Range
    Serum (n=5) 90 87-95
    EDTA plasma (n=4) 101 103-106
  • 標準曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    ng/ml OD1 OD2 Average Corrected
    60 2.588 2.787 2.688 2.535
    30 2.169 2.236 2.203 2.050
    15 1.674 1.744 1.709 1.556
    7.5 1.322 1.223 1.273 1.120
    3.75 0.752 0.744 0.748 0.595
    1.8 0.363 0.375 0.369 0.216
    0.9 0.261 0.255 0.258 0.105
    0 0.149 0.156 0.153 　
  • 數據處理：
  • 貨期：
    3-5 working days

產品評價

靶點詳情

  • 功能：
    Plays a role in B-cell proliferation and differentiation.
  • 基因功能參考文獻：
    1. Interferon-alpha-induced CD100 expression on naive CD8(+) T cells enhances antiviral responses to hepatitis C infection through CD72 signal transduction. PMID: 28222623
    2. Increased soluble CD72 in systemic lupus erythematosus is in association with disease activity and lupus nephritis PMID: 26883681
    3. CD72 expression on activated B cells of SLE patients was significantly lower than that of normal controls. sema3A enhanced CD72 expression of B cells, but it was still lower in SLE patients than in normal individuals. PMID: 24461079
    4. data demonstrated aberrant expression of CD72 exists on B cells of myasthenia gravis and multiple sclerosis patients and expression level of CD72 molecule has a significantly negative correlation with anti-AchR antibody levels in myasthenia gravis PMID: 23184497
    5. regulates serum immunoglobulin leveln and disease resistance in systemic lupus erythematosus PMID: 23268649
    6. CD72 mRNA expression level correlates with Sema4D expression in peripheral blood mononuclear cells in immune thrombocytopenia. PMID: 22111667
    7. CD100, CD72 and CD45 were expressed in placenta and exhibited different mRNA and protein levels in normal pregnancy and miscarriage. Protein levels were highly dysregulated around 10 weeks of gestation in first and second miscarriage placentas. PMID: 22606231
    8. CD100-CD72 interaction can be the mechanism by which NK cell communicate with B cells. PMID: 17786190
    9. Data show that ligation of CD72 with the BU40, or with rCD100 negatively regulates KIT-mediated mast cell proliferation, chemotaxis, and chemokine production. PMID: 20100931
    10. results indicated that the presence of CD72-*2 allele decreases risk for human systemic lupus erythematosus conferred by FCGR2B-232Thr, possibly by increasing the AS isoform of CD72 PMID: 15459183
    11. CD72 is a key molecule in regulating mature B cell differentiation; CD72 signaling reduces the expression of X-box binding protein 1 in B cells PMID: 16047337
    12. increased nucleotide mutation of CD72 mRNA accounts for the decreased expression level of CD72 in B cells, and it might be related to hyperactivity of B cells in patients with SLE PMID: 17121583
    13. CD72 polymorphisms are associated with age of appearing clinical manifestations in idiopathic thrombocytopenic purpura in Chinese patients. PMID: 18071878

    顯示更多

    收起更多

  • 亞細胞定位：
    Membrane; Single-pass type II membrane protein.
  • 組織特異性：
    Pre-B-cells and B-cells but not terminally differentiated plasma cells.
  • 數據庫鏈接：

    HGNC: 1696

    OMIM: 107272

    KEGG: hsa:971

    STRING: 9606.ENSP00000259633

    UniGene: Hs.116481



主站蜘蛛池模板： 日韩免费无码专区精品观看| 九九热爱视频精品| 国产欧美日韩视频一区二区三区| 男女免费观看在线爽爽爽视频| 2022国产成人精品视频人 | 中国老熟女重囗味hdxx| 在线a亚洲视频播放在线观看| 欧美性猛交xxxx黑人| 男女无遮挡猛进猛出免费观看视频 | 国产午夜不卡片免费视频| 久久成人国产精品| 少妇邻居内射在线| 美女被张开双腿日出白浆| 亚洲国产欧美中文丝袜日韩| a亚洲va欧美va国产综合| 日本高清视频www夜色资源| 国产伦人人人人人人性| 亚洲色欲色欲www在线看| 五月丁香啪啪| 国产成人久久a免费观看| 亚洲另类欧美在线电影| 四虎影视在线观看2413| 大学生高潮无套内谢视频| 国产精品午夜福利不卡| 国产精品992tv在线观看| 在线精品国产成人综合| 中文乱码人妻系列一区二区| 国偷自产一区二区三区在线视频| 精品一区二区三区四区五区六区| 中文字幕日韩精品一区二区三区| 中文字幕卡二和卡三的视频| 伊人精品成人久久综合97 | 免费三级现频在线观看免费| 无码国产玉足脚交极品播放| 国产吃奶在线观看| 国产成人一区二区三区影院动漫| 超碰曰口干天天种夜夜爽| 日本无遮挡吸乳呻吟视频| 中文字幕无码乱人伦| 国产99视频精品免费专区 | 好男人www社区|