Dog Interleukin-1 receptor antagonist protein(IL1RN) ELISA kit
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中文名稱:犬白介素1受體拮抗劑蛋白(IL1RN)酶聯免疫試劑盒
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貨號:CSB-EL011628DO
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規格:96T/48T
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價格:¥4200/¥3000
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其他:
產品詳情
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產品描述:犬白介素1受體拮抗劑蛋白(IL1RN)酶聯免疫試劑盒(CSB-EL011628DO)為雙抗夾心法ELISA試劑盒,定量檢測血清、血漿、組織勻漿樣本中的IL1RN含量。IL1RN基因編碼白介素 - 1受體拮抗劑。其背景在于它可調節炎癥反應,避免過度炎癥。研究機制方面,它能競爭性結合白介素 - 1受體,阻斷白介素 - 1的生物學活性,在多種炎癥性疾病如類風濕關節炎的發病機制和治療研究里備受關注。試劑盒檢測范圍為15.6 pg/ml-1000 pg/ml,本試劑盒的應用場景涵蓋犬類炎癥性疾病模型研究、免疫調節機制探索以及藥效評價實驗中IL1RN表達水平的動態監測,例如通過檢測感染或免疫刺激后血清、組織中的IL1RN濃度變化,解析炎癥反應與拮抗系統的相互作用。本品僅用于科研,不用于臨床診斷,產品具體參數及操作步驟詳見產品說明書。
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別名:IL1RNInterleukin-1 receptor antagonist protein ELISA Kit; IL-1RN ELISA Kit; IL-1ra ELISA Kit; IRAP ELISA Kit; IL1 inhibitor ELISA Kit
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縮寫:IL1RN
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Uniprot No.:
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種屬:Canis lupus familiaris (Dog) (Canis familiaris)
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樣本類型:serum, plasma, tissue homogenates
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檢測范圍:15.6 pg/ml-1000 pg/ml
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靈敏度:3.9 pg/ml
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反應時間:1-5h
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樣本體積:50-100ul
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檢測波長:450 nm
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研究領域:Others
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測定原理:quantitative
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測定方法:Sandwich
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數據處理:
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貨期:3-5 working days
相關產品
靶點詳情
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功能:Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity.
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基因功能參考文獻:
- This study showed that the IL-1Ra:IL-1beta protein ratio was negatively correlated with clinical severity in dogs with inflammatory bowel disease. PMID: 22483380
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亞細胞定位:Secreted.
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蛋白家族:IL-1 family
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數據庫鏈接:
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