在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 試劑盒
  3. 酶聯(lián)免疫試劑盒
  4. Chicken Transforming Growth factor β1,TGF-β1 ELISA kit

Chicken Transforming Growth factor β1,TGF-β1 ELISA kit

  • 中文名稱：
    雞轉(zhuǎn)化生長因子β1(TGF-β1)酶聯(lián)免疫試劑盒
  • 貨號：
    CSB-E09875Ch
  • 規(guī)格：
    96T/48T
  • 價格：
    ￥4200/￥3000
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    雞轉(zhuǎn)化生長因子β1(TGF-β1)酶聯(lián)免疫試劑盒（CSB-E09875Ch）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的TGFB1含量。TGFB1是重要的靶點，它是一種多功能細胞因子。在細胞生長、分化、凋亡等過程中發(fā)揮關(guān)鍵作用。其異常表達與多種疾病如腫瘤、纖維化等密切相關(guān)。研究機制主要圍繞其信號通路展開，旨在調(diào)控其活性來治療相關(guān)疾病。試劑盒檢測范圍為0.312 ng/mL-20 ng/mL，適用于家禽免疫學(xué)基礎(chǔ)研究、病理模型建立及生物標志物分析，特別在探究禽類傳染性疾病、疫苗效價評估或應(yīng)激反應(yīng)機制等科研場景中，能夠為實驗提供穩(wěn)定可靠的定量數(shù)據(jù)支持。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
  • 別名：
    TGFB1 ELISA Kit; Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide ELISA Kit; LAP); Transforming growth factor beta-1 ELISA Kit; TGF-beta-1)] ELISA Kit
  • 縮寫：
  • Uniprot No.：
  • 種屬：
    Gallus gallus (Chicken)
  • 樣本類型：
    serum, plasma, tissue homogenates
  • 檢測范圍：
    0.312 ng/mL-20 ng/mL
  • 靈敏度：
    0.078 ng/mL
  • 反應(yīng)時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領(lǐng)域：
    Signal Transduction
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of chicken TGF-β1 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    　SampleSerum(n=4)
    1:1Average %93
    Range %84-97
    1:2Average %95
    Range %84-98
    1:4Average %96
    Range %89-103
    1:8Average %95
    Range %85-100
  • 回收率：
    The recovery of chicken TGF-β1 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample TypeAverage % RecoveryRange
    Serum (n=5) 9084-97
    EDTA plasma (n=4)9792-102
  • 標準曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    ng/mlOD1OD2AverageCorrected
    202.011 2.105 2.058 1.965
    101.790 1.828 1.809 1.716
    51.466 1.527 1.497 1.404
    2.51.149 1.163 1.156 1.063
    1.250.795 0.854 0.825 0.732
    0.6250.433 0.425 0.429 0.336
    0.3120.264 0.255 0.260 0.167
    00.095 0.091 0.093 　
  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

產(chǎn)品評價

靶點詳情

  • 功能：
    Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.; Required to maintain the Transforming growth factor beta-1 (TGF-beta-1) chain in a latent state during storage in extracellular matrix. Associates non-covalently with TGF-beta-1 and regulates its activation via interaction with 'milieu molecules', such as LTBP1, LRRC32/GARP and LRRC33/NRROS, that control activation of TGF-beta-1. Interaction with integrins (ITGAV:ITGB6 or ITGAV:ITGB8) results in distortion of the Latency-associated peptide chain and subsequent release of the active TGF-beta-1.; Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration. Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains remain non-covalently linked rendering TGF-beta-1 inactive during storage in extracellular matrix. At the same time, LAP chain interacts with 'milieu molecules', such as LTBP1, LRRC32/GARP and LRRC33/NRROS that control activation of TGF-beta-1 and maintain it in a latent state during storage in extracellular milieus. TGF-beta-1 is released from LAP by integrins (ITGAV:ITGB6 or ITGAV:ITGB8): integrin-binding to LAP stabilizes an alternative conformation of the LAP bowtie tail and results in distortion of the LAP chain and subsequent release of the active TGF-beta-1. Once activated following release of LAP, TGF-beta-1 acts by binding to TGF-beta receptors (TGFBR1 and TGFBR2), which transduce signal. While expressed by many cells types, TGF-beta-1 only has a very localized range of action within cell environment thanks to fine regulation of its activation by Latency-associated peptide chain (LAP) and 'milieu molecules'. Plays an important role in bone remodeling: acts as a potent stimulator of osteoblastic bone formation. Can promote either T-helper 17 cells (Th17) or regulatory T-cells (Treg) lineage differentiation in a concentration-dependent manner. Can induce epithelial-to-mesenchymal transition (EMT) and cell migration in various cell types.
  • 亞細胞定位：
    [Latency-associated peptide]: Secreted, extracellular space, extracellular matrix.; [Transforming growth factor beta-1]: Secreted.
  • 蛋白家族：
    TGF-beta family
  • 數(shù)據(jù)庫鏈接：

    UniGene: Gga.929



主站蜘蛛池模板： 精品国产av无码一区二区三区| 国产在线不卡精品网站| 午夜精品久久久久久久喷水| 久久久久无码精品亚洲日韩| 丁香五月亚洲综合在线| 亚洲精品国产精品无码国模| 欧美精品a∨在线观看| 日韩精品久久久久久免费 | 日韩在线一区二区三区免费视频| 国产成人亚洲精品无码电影| 韩国精品久久久久久无码| 中文字幕无码免费久久99| 午夜片无码区私人影院| 久久人人爽人人爽人人片dvd| 国产成久久免费精品av片| 中文字幕一区在线观看视频| 日韩熟女精品一区二区三区| 国产午费午夜福利200集| 国产69精品久久久久孕妇| 国产裸体美女永久免费无遮挡| 久久躁狠狠躁夜夜av| 天天做天天爱天天综合网2021| 日本国产成人国产在线播放| 亚洲老熟女与小伙bbwtv| 激情五月婷婷| 精品无码av无码专区| 在线|国产精品女主播阳台| 欧美国产日本高清不卡| 99视频偷窥在线精品国自产拍| 99精品视频在线观看婷婷| 亚洲国产精品无码中文字| 国产呻吟久久久久久久92| 亚洲精品久久久久久无码色欲四季 | 久久不见久久见免费影院www| av无码久久久久久不卡网站| 日日噜噜大屁股熟妇| 久久久久国色av免费观看性色| 亚洲成av人综合在线观看| 日本国产网曝视频在线观看| 四虎精品免费永久免费视频| 好吊色欧美一区二区三区视频|