在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 試劑盒
  3. 酶聯(lián)免疫試劑盒
  4. Chicken Transforming Growth factor β1,TGF-β1 ELISA kit

Chicken Transforming Growth factor β1,TGF-β1 ELISA kit

  • 中文名稱：
    雞轉(zhuǎn)化生長因子β1(TGF-β1)酶聯(lián)免疫試劑盒
  • 貨號：
    CSB-E09875Ch
  • 規(guī)格：
    96T/48T
  • 價格：
    ￥4200/￥3000
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    雞轉(zhuǎn)化生長因子β1(TGF-β1)酶聯(lián)免疫試劑盒（CSB-E09875Ch）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的TGFB1含量。TGFB1是重要的靶點，它是一種多功能細胞因子。在細胞生長、分化、凋亡等過程中發(fā)揮關(guān)鍵作用。其異常表達與多種疾病如腫瘤、纖維化等密切相關(guān)。研究機制主要圍繞其信號通路展開，旨在調(diào)控其活性來治療相關(guān)疾病。試劑盒檢測范圍為0.312 ng/mL-20 ng/mL，適用于家禽免疫學(xué)基礎(chǔ)研究、病理模型建立及生物標志物分析，特別在探究禽類傳染性疾病、疫苗效價評估或應(yīng)激反應(yīng)機制等科研場景中，能夠為實驗提供穩(wěn)定可靠的定量數(shù)據(jù)支持。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
  • 別名：
    TGFB1 ELISA Kit; Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide ELISA Kit; LAP); Transforming growth factor beta-1 ELISA Kit; TGF-beta-1)] ELISA Kit
  • 縮寫：
  • Uniprot No.：
  • 種屬：
    Gallus gallus (Chicken)
  • 樣本類型：
    serum, plasma, tissue homogenates
  • 檢測范圍：
    0.312 ng/mL-20 ng/mL
  • 靈敏度：
    0.078 ng/mL
  • 反應(yīng)時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領(lǐng)域：
    Signal Transduction
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of chicken TGF-β1 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    　SampleSerum(n=4)
    1:1Average %93
    Range %84-97
    1:2Average %95
    Range %84-98
    1:4Average %96
    Range %89-103
    1:8Average %95
    Range %85-100
  • 回收率：
    The recovery of chicken TGF-β1 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample TypeAverage % RecoveryRange
    Serum (n=5) 9084-97
    EDTA plasma (n=4)9792-102
  • 標準曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    ng/mlOD1OD2AverageCorrected
    202.011 2.105 2.058 1.965
    101.790 1.828 1.809 1.716
    51.466 1.527 1.497 1.404
    2.51.149 1.163 1.156 1.063
    1.250.795 0.854 0.825 0.732
    0.6250.433 0.425 0.429 0.336
    0.3120.264 0.255 0.260 0.167
    00.095 0.091 0.093 　
  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

產(chǎn)品評價

靶點詳情

  • 功能：
    Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.; Required to maintain the Transforming growth factor beta-1 (TGF-beta-1) chain in a latent state during storage in extracellular matrix. Associates non-covalently with TGF-beta-1 and regulates its activation via interaction with 'milieu molecules', such as LTBP1, LRRC32/GARP and LRRC33/NRROS, that control activation of TGF-beta-1. Interaction with integrins (ITGAV:ITGB6 or ITGAV:ITGB8) results in distortion of the Latency-associated peptide chain and subsequent release of the active TGF-beta-1.; Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration. Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains remain non-covalently linked rendering TGF-beta-1 inactive during storage in extracellular matrix. At the same time, LAP chain interacts with 'milieu molecules', such as LTBP1, LRRC32/GARP and LRRC33/NRROS that control activation of TGF-beta-1 and maintain it in a latent state during storage in extracellular milieus. TGF-beta-1 is released from LAP by integrins (ITGAV:ITGB6 or ITGAV:ITGB8): integrin-binding to LAP stabilizes an alternative conformation of the LAP bowtie tail and results in distortion of the LAP chain and subsequent release of the active TGF-beta-1. Once activated following release of LAP, TGF-beta-1 acts by binding to TGF-beta receptors (TGFBR1 and TGFBR2), which transduce signal. While expressed by many cells types, TGF-beta-1 only has a very localized range of action within cell environment thanks to fine regulation of its activation by Latency-associated peptide chain (LAP) and 'milieu molecules'. Plays an important role in bone remodeling: acts as a potent stimulator of osteoblastic bone formation. Can promote either T-helper 17 cells (Th17) or regulatory T-cells (Treg) lineage differentiation in a concentration-dependent manner. Can induce epithelial-to-mesenchymal transition (EMT) and cell migration in various cell types.
  • 亞細胞定位：
    [Latency-associated peptide]: Secreted, extracellular space, extracellular matrix.; [Transforming growth factor beta-1]: Secreted.
  • 蛋白家族：
    TGF-beta family
  • 數(shù)據(jù)庫鏈接：

    UniGene: Gga.929



主站蜘蛛池模板： a级大胆欧美人体大胆666| 好男人社区www在线官网| 无码中文av有码中文a| 婷婷色香五月综合缴缴情| 无码少妇一区二区三区视频| 国产成人无码一区二区在线观看 | 日韩精品国产另类专区| 亚洲精品乱码久久久久蜜桃| 亚洲风情亚aⅴ在线发布| 欧美疯狂性受xxxxx喷水| 色综合久久久久综合99| 人妻系列无码专区无码中出| 久久不见久久见免费影院www| 美女av一区二区三区| av蓝导航精品导航| 一区二区三区乱码在线 | 欧洲| 国产精品视频永久免费播放| 狠狠亚洲婷婷综合色香五月排名 | 国产亚洲无线码一区二区| 国产成人美女视频网站| 18无码粉嫩小泬无套在线观看 | 少妇挑战三个黑人惨叫4p国语| 国产aⅴ精品一区二区三区尤物| 国产精品久久国产精麻豆99网站| 免费人成在线观看网站| 亚洲成av人片在线观看| 国产午夜成人无码免费看不卡| 男女做爰无遮挡性视频| 人妻去按摩店被黑人按中出| 色综合久久久久无码专区| 亚洲乱码日产精品bd在线| 国产精品久久久久高潮| 成人免费的视频| 国产精品亚洲精品一区二区| 天堂最新版在线www官网中文地址| 日本免费大黄在线观看| 精品噜噜噜噜久久久久久久久| 亚洲偷精品国产五月丁香麻豆| 国产精品免费视频网站| 水蜜桃av无码| 成人做爰视频www网站|