在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 試劑盒
  3. 酶聯(lián)免疫試劑盒
  4. Chicken Transforming Growth factor β1,TGF-β1 ELISA kit

Chicken Transforming Growth factor β1,TGF-β1 ELISA kit

  • 中文名稱：
    雞轉(zhuǎn)化生長因子β1(TGF-β1)酶聯(lián)免疫試劑盒
  • 貨號：
    CSB-E09875Ch
  • 規(guī)格：
    96T/48T
  • 價格：
    ￥4200/￥3000
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    雞轉(zhuǎn)化生長因子β1(TGF-β1)酶聯(lián)免疫試劑盒（CSB-E09875Ch）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的TGFB1含量。TGFB1是重要的靶點，它是一種多功能細胞因子。在細胞生長、分化、凋亡等過程中發(fā)揮關(guān)鍵作用。其異常表達與多種疾病如腫瘤、纖維化等密切相關(guān)。研究機制主要圍繞其信號通路展開，旨在調(diào)控其活性來治療相關(guān)疾病。試劑盒檢測范圍為0.312 ng/mL-20 ng/mL，適用于家禽免疫學(xué)基礎(chǔ)研究、病理模型建立及生物標志物分析，特別在探究禽類傳染性疾病、疫苗效價評估或應(yīng)激反應(yīng)機制等科研場景中，能夠為實驗提供穩(wěn)定可靠的定量數(shù)據(jù)支持。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
  • 別名：
    TGFB1 ELISA Kit; Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide ELISA Kit; LAP); Transforming growth factor beta-1 ELISA Kit; TGF-beta-1)] ELISA Kit
  • 縮寫：
  • Uniprot No.：
  • 種屬：
    Gallus gallus (Chicken)
  • 樣本類型：
    serum, plasma, tissue homogenates
  • 檢測范圍：
    0.312 ng/mL-20 ng/mL
  • 靈敏度：
    0.078 ng/mL
  • 反應(yīng)時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領(lǐng)域：
    Signal Transduction
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of chicken TGF-β1 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    　SampleSerum(n=4)
    1:1Average %93
    Range %84-97
    1:2Average %95
    Range %84-98
    1:4Average %96
    Range %89-103
    1:8Average %95
    Range %85-100
  • 回收率：
    The recovery of chicken TGF-β1 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample TypeAverage % RecoveryRange
    Serum (n=5) 9084-97
    EDTA plasma (n=4)9792-102
  • 標準曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    ng/mlOD1OD2AverageCorrected
    202.011 2.105 2.058 1.965
    101.790 1.828 1.809 1.716
    51.466 1.527 1.497 1.404
    2.51.149 1.163 1.156 1.063
    1.250.795 0.854 0.825 0.732
    0.6250.433 0.425 0.429 0.336
    0.3120.264 0.255 0.260 0.167
    00.095 0.091 0.093 　
  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

產(chǎn)品評價

靶點詳情

  • 功能：
    Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.; Required to maintain the Transforming growth factor beta-1 (TGF-beta-1) chain in a latent state during storage in extracellular matrix. Associates non-covalently with TGF-beta-1 and regulates its activation via interaction with 'milieu molecules', such as LTBP1, LRRC32/GARP and LRRC33/NRROS, that control activation of TGF-beta-1. Interaction with integrins (ITGAV:ITGB6 or ITGAV:ITGB8) results in distortion of the Latency-associated peptide chain and subsequent release of the active TGF-beta-1.; Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration. Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains remain non-covalently linked rendering TGF-beta-1 inactive during storage in extracellular matrix. At the same time, LAP chain interacts with 'milieu molecules', such as LTBP1, LRRC32/GARP and LRRC33/NRROS that control activation of TGF-beta-1 and maintain it in a latent state during storage in extracellular milieus. TGF-beta-1 is released from LAP by integrins (ITGAV:ITGB6 or ITGAV:ITGB8): integrin-binding to LAP stabilizes an alternative conformation of the LAP bowtie tail and results in distortion of the LAP chain and subsequent release of the active TGF-beta-1. Once activated following release of LAP, TGF-beta-1 acts by binding to TGF-beta receptors (TGFBR1 and TGFBR2), which transduce signal. While expressed by many cells types, TGF-beta-1 only has a very localized range of action within cell environment thanks to fine regulation of its activation by Latency-associated peptide chain (LAP) and 'milieu molecules'. Plays an important role in bone remodeling: acts as a potent stimulator of osteoblastic bone formation. Can promote either T-helper 17 cells (Th17) or regulatory T-cells (Treg) lineage differentiation in a concentration-dependent manner. Can induce epithelial-to-mesenchymal transition (EMT) and cell migration in various cell types.
  • 亞細胞定位：
    [Latency-associated peptide]: Secreted, extracellular space, extracellular matrix.; [Transforming growth factor beta-1]: Secreted.
  • 蛋白家族：
    TGF-beta family
  • 數(shù)據(jù)庫鏈接：

    UniGene: Gga.929



主站蜘蛛池模板： 在线精品视频一区二区三四| 在线观看麻豆国产成人av在线播放 | 天堂va欧美ⅴa亚洲va| 亚洲学生妹高清av| 亚洲欧美另类久久久精品| 欧美性开放情侣网站| 久拍国产在线观看| 国产无遮挡18禁无码网站免费| 国产欧美高清在线观看| 综合三区后入内射国产馆| 日韩午夜理论免费tv影院| 99热精国产这里只有精品| 性高湖久久久久久久久aaaaa| 少妇午夜啪爽嗷嗷叫视频| 台湾无码av一区二区三区| 日本一区午夜艳熟免费| 午夜不卡久久精品无码免费| 在线亚洲欧美日韩精品专区| 免费人成黄页在线观看国产| 日韩一区二区三区高清电影| 三男一女吃奶添下面视频| 亚洲国产精品13p| 国产成人精品s8视频| 久久精品午夜福利| 国产成人a人亚洲精品无码 | 777精品久无码人妻蜜桃| 久久精品国产99精品亚洲| 真人床震高潮全部视频免费| 国产大屁股喷水视频在线观看| 免费无码一区二区三区蜜桃大| 97色伦午夜国产亚洲精品| 性色av无码不卡中文字幕| 乱子轮熟睡1区| 亚洲精品国产一区二区三| 国产乱了伦视频大全亚琴影院| 国产精品美女久久久久久久| 五月色丁香婷婷网蜜臀av| 成人无码视频免费播放| 真人作爱免费视频| 国产一卡三卡四卡无卡精品| 国产免费不卡av在线播放|