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Bovine Plasminogen(PLG) ELISA kit

  • 中文名稱:
    牛纖維蛋白溶解酶原(PLG)酶聯(lián)免疫試劑盒
  • 貨號:
    CSB-EL018188BO
  • 規(guī)格:
    96T/48T
  • 價格:
    ¥4200/¥3000
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品描述:
    牛纖維蛋白溶解酶原(PLG)酶聯(lián)免疫試劑盒(CSB-EL018188BO)為競爭法ELISA試劑盒,定量檢測血清、血漿、組織勻漿樣本中的PLG含量。試劑盒檢測范圍為62.5 ng/mL-4000 ng/mL,靈敏度為15.6 ng/mL。本產(chǎn)品適用于牛源樣本的PLG水平監(jiān)測,支持凝血相關(guān)疾病模型研究、纖溶系統(tǒng)調(diào)控機制探索,在獸醫(yī)基礎(chǔ)研究、畜牧業(yè)生物標(biāo)志物分析及抗凝血藥物研發(fā)中具有應(yīng)用價值。本品僅用于科研,不用于臨床診斷,產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
  • 別名:
    PLG ELISA Kit; Plasminogen ELISA Kit; EC 3.4.21.7) [Cleaved into: Plasmin heavy chain A; Activation peptide; Plasmin heavy chain A ELISA Kit; short form; Plasmin light chain B] ELISA Kit
  • 縮寫:
  • Uniprot No.:
  • 種屬:
    Bos taurus (Bovine)
  • 樣本類型:
    serum, plasma, tissue homogenates
  • 檢測范圍:
    62.5 ng/mL-4000 ng/mL
  • 靈敏度:
    15.6 ng/mL
  • 反應(yīng)時間:
    1-5h
  • 樣本體積:
    50-100ul
  • 檢測波長:
    450 nm
  • 研究領(lǐng)域:
    Cardiovascular
  • 測定原理:
    quantitative
  • 測定方法:
    Competitive
  • 精密度:

  • 線性度:

  • 回收率:

  • 標(biāo)準(zhǔn)曲線:

  • 數(shù)據(jù)處理:
  • 貨期:
    3-5 working days

產(chǎn)品評價

靶點詳情

  • 最新研究進展:
    PLG是一種廣泛存在于人體內(nèi)的血漿蛋白,最近的研究表明PLG在多種疾病的發(fā)生和發(fā)展中可能發(fā)揮著重要的作用。
  • 功能:
    Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells.
  • 基因功能參考文獻:
    1. SUPA formed a higher avidity complex (118-fold) with bovine Pg than with human Pg and non-proteolytically activated bovine but not human Pg. PMID: 22518846
    2. The plasminogen/plasminogen activator/plasmin system is activated during gamete interaction and regulates the sperm entry into the oocyte. PMID: 22177313
    3. The current study suggests the existence of an active TNF-alpha-plasminogen-plasmin autocrine/paracrine loop on the massively infiltrated polymorphonuclear neutrophils inside udders of drying-off cows. PMID: 19638263
    4. examination of interaction with streptococcal plasminogen activator PauA PMID: 15351638
  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Peptidase S1 family, Plasminogen subfamily
  • 數(shù)據(jù)庫鏈接:

    KEGG: bta:280897

    STRING: 9913.ENSBTAP00000001674

    UniGene: Bt.306



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